5.10.2026

1. Introduction to laboratory techniques/ Calculations

1. 1. Use of laboratory equipment
   2. Titration of aspirin

 12.10.2026

2. Serum proteins

1. Serum protein electrophoresis.
2. Hyperproteinemia and hypoproteinemia,
3. Monoclonal and polyclonal gammopathy,
4. Acute phase proteins.

 19.10.2026  

3. Clinically important enzymes

1. 1. Lactate dehydrogenase (LDH), Alkaline phosphatase (AP), Acid phosphatase (ACP), Prostatic acid phosphatase (ACPP, ACP3), Tartrate-resistant acid phosphatase (ACP5), glutamic-pyruvic transaminase (ALT, SGPT), serum glutamic-oxaloacetic transaminase (AST, SGOT), Gamma-glutamyl transpeptidase (GGT), Creatine kinase (CK), amylase, lipase
   2. Non-enzymatic markers: Prostate specific antigen (PSA), Cardiac troponin I (cTnI) and T (cTnT)

26.10.2026    

 4. Hormones: Endocrinology tests, free and total fractions of hormones, metabolites of hormones, specialized tests: urinary excretion of 5-HIAA, the 24-hour urine collection for catecholamines and hormone metabolites. 

2.11.2026

No Lab

9.11.2026

 5.  Estimation of fasting and postprandial blood glucose, Oral glucose tolerance test (OGTT), glycated hemoglobin. Definition and classification of diabetes mellitus, impaired glucose tolerance (IGT), impaired fasting glucose (IFG).

16.11.2026

6. Alcohol and drugs metabolism in the body. The effects of abuse. Drug test, alcohol concentration in blood.

23.11.2026

7. Lipids: Total cholesterol, LDL, HDL, triglycerides.

1. Laboratory criteria of dyslipidemia, Friedewald formula. Primary and secondary lipid disorders.
   
2. Lipids: electrophoresis, specialized tests: ApoB100, ApoA1, electrophoresis.

30.11.2026

8. Reactive oxygen species – characteristics. ROS in the regulation of physiological processes. MDA test in human plasma

7.12.2026

9. Markers of nitrogen metabolism and kidney function: creatinine, uric acid, urea, rest nitrogen, amino acids. 

14.12.2026

Colloquium II  (from lectures and seminars) 14th of December at 12:00 in the lecture hall 

11.01.2027

10. Hemoglobin and bile pigments: metabolism, excretion, the importance in clinical diagnostic of anemia and jaundice.

1. Jaundice: hemolytic, cholestatic and hepatic.
2. Iron metabolism markers (transferrin, ferritin, total iron binding capacity [TIBC], transferrin saturation, transferrin receptors), ceruloplasmin.

 18.01.2027